徐晓虹
发布时间: 2014-02-24 浏览次数: 1443
 

 

   

 

     徐晓虹教授,博士,硕士生导师。主要研究方向:学习记忆的神经生物学机制和环境内分泌干扰物对脑和行为发育的影响。   

近几年承担的研究课题: 

  1. 主持国家自然科学基金项目(2015~2018):双酚A对雄激素调节神经行为和突触可塑性的影响及其机制研究
  2. 主持国家自然科学基金项目(2012~2015): 双酚A对成年神经行为和突触可塑性的影响及其机制研究(81172627
  3. 主持国家自然科学基金项目(2009~2011): 双酚A发育中脑内NMDA受体的影响及其机制研究(30872087
  4. 主持国家自然科学基金项目(2008):双酚A对发育中脑内NMDA受体的影响(30771783)  
  5. 主持省自然科学基金重点项目(2010~2013):环境雌激素对神经元树突发育和突触发生的影响(Z2090955)

 近几年代表性学术论文:      

  1. Xiaohong Xu*, Fangni Dong, Yanling Yang, Yu Wang, Ran Wang, Xiuying Shen. Sex-specific effects of long-term exposure to bisphenol-A on anxiety- and depression-like behaviors in adult mice. Chemosphere, 2015, 120, 258-266
  2. Qin Zhang, Xiaohong Xu*, Tao Li, Yang Lu, Qin Ruan, Yingjun Lu, Qinwen Wang, Fangni Dong, Yanling Yang, Guangxia Zhang. Exposure to bisphenol-A affects fear memory and histone acetylation of the hippocampus in adult mice. Hormones and Behavior 2014, 65(2):106–113.  
  3. Xiaohong Xu*, Yang Lu, Guangxia Zhang, Lei Chen, Dong Tian, Xiuying Shen, Yanling Yang, Fanni Dong. Bisphenol A promotes dendritic morphogenesis of hippocampal neurons through estrogen receptor-mediated ERK1/2 signal pathway. Chemosphere, 2014, 96(8):129-137
  4. Xiaohong Xu*, Xingyi Liu, Qin Zhang, Guangxia Zhang, Yingjun Lu, Qin Ruan, Fangni Dong, Yanling Yang. Sex-specific effects of bisphenol-A on memory and synaptic structural modification in hippocampus of adult mice. Hormones and Behavior 2013, 63:766–775.
  5. Xiaohong Xu*, Lingdan Xie, Xing Hong, Qin Ruan, Hongfei Lu, Qin Zhang, Guangxia Zhang, Xingyi Liu. Perinatal exposure to bisphenol-A inhibits synaptogenesis and affects the synaptic morphological development in offspring male mice. Chemosphere, 2013, 91(8):1073-1081   
  6. 杨艳玲, 徐晓虹*. 增塑剂DEHP的神经和行为发育毒性. 心理科学进展 2013, 21(6): 1007–1013  
  7. Xiaohong Xu*, Xing Hong, Lingdan Xie, Tao Li, Yujie Yang, Qin Zhang,Guangxia Zhang, Xingyi Liu. Gestational and lactational exposure to bisphenol-A affects anxiety- and depression-like behaviors in mice. Horm & Behav, 2012, 62:480-490  
  8. 杨宇杰,徐晓虹*,洪星,谢灵丹,余奇静,田栋。妊娠期和哺乳期双酚A暴露对幼年子代小鼠焦虑和抑郁行为的影响。生物物理学报  2012, 28(2): 209-215  
  9. Xiaohong Xu*, Dong Tian, Xing Hong, Lei Chen, Lingdan Xie. Sex-specific influence of exposure to bisphenol-A between adolescence and young adulthood on mouse behaviors. Neuropharmacology 2011, 614: 565-573.  
  10. Xiaohong Xu*, Tao Li, Qingqing Luo, Xing Hong, Lingdan Xie, Dong Tian. Bisphenol-A rapidly enhanced passive avoidance memory and phosphorylation of NMDA receptor subunits in hippocampus of young rats. Toxicology & Applied Pharmacology 2011, 2552:221-228
  11. Xiaohong Xu*, Yinping Ye, Tao Li, et al. Bisphenol-A rapidly promotes dynamic changes in hippocampal dendritic morphology through estrogen receptor-mediated pathway by concomitant phosphorylation of NMDA receptor subunit NR2B. Toxicology and Applied Pharmacology. 2010, 249(2):188-196  
  12. Xiao-hong Xu*, Jing Zhang, Ya-min Wang, et al. Perinatal exposure to bisphenol-A impairs learning-memory by concomitant down-regulation of N-methyl-d-aspartate receptors of hippocampus in male offspring mice. Hormones & Behavior, 2010, 58(2): 326-333
  13. Xiao-Hong Xu*, Ya-Min Wang, Jing Zhang, et al. Perinatal exposure to bisphenol-A changes N-methyl-D-aspartate receptor expression in hippocampus of male rat offspring. Environmental Toxicology and Chemistry 2010, 29(1):176-181  
  14. 王亚民,徐晓虹*,张婧,等。围产期母体染毒双酚A 对雄性子代脑内雌激素受体和芳香酶表达的影响。生物物理学报 2009, 256:424-429   
  15. 陈蕾, 徐晓虹*,田栋. 环境雌激素双酚A对脑和行为发育的影响. 中国科学C辑:生命科学,2009, 3912):1111-1119           
  16. 张婧,徐晓虹*,王亚民,等。围生期双酚A暴露对不同性别子代小鼠行为的影响. 心理学报 2009, 41(9):832-841     
  17. 王亚民,徐晓虹*,张婧,等。围产期母鼠染毒双酚A对雄性子代脑内谷氨酸N-甲基-D-天冬氨酸型受体发育的影响。生物物理学报 2009, 25(2):99-105          

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