徐晓虹
发布时间: 2014-02-24 浏览次数: 3083
 


徐晓虹教授,博士,双龙学者特聘教授,博士生导师。

主要研究方向:行为的神经生物学机制和环境内分泌干扰物对脑和行为发育的影响。主持国家自然科学基金面上项目5项,浙江省自然科学基金重点项目1项和其它省级项目;发表论文100余篇。

主要承担的研究课题:

1 主持国家自然科学基金项目(2018~2021):青春期双酚A暴露对社会行为的影响及其神经机制

2 主持国家自然科学基金项目(2015~2018):双酚A对雄激素调节神经行为和突触可塑性的影响及其机制研究

3 主持国家自然科学基金项目(2012~2015):双酚A对成年神经行为和突触可塑性的影响及其机制研究

4 主持国家自然科学基金项目(2009~2011):双酚A对发育中脑内NMDA受体的影响及其机制研究

5 主持国家自然科学基金项目(2008):双酚A对发育中脑内NMDA受体的影响

6 主持省自然科学基金重点项目(2010~2013):环境雌激素对神经元树突发育和突触发生的影响

近几年代表性学术论文:

1 Yvfeng Liang, Jiahong Li, Tao Jin, Ting Gu, Qingjie Zhu, Yizhong Hu, Yang Yang, Jisui Li, Donghong Wu, Kesheng Jiang, Xiaohong Xu*. Bisphenol-A inhibits improvement of testosterone in anxiety- and depression-like behaviors in gonadectomied male mice. Horm & Behav. 2018, 102:129-138

2 Yang Yang, Zhaoqing Fang, Yuhua Dai, Yu Wang, Yufeng Liang, Xiaoyu Zhong, Qinwen Wang, Yizhong Hu, Zigui Zhang, Donghong Wu, Xiaohong Xu*. Bisphenol-A antagonizes the rapidly modulating effect of DHT on spinogenesis and long-term potentiation of hippocampal neurons. Chemosphere. 2018, 195: 567-575

3 Zhaoqing Fang, Qingjie Zhu, Ting Gu, Xiuying Shen, Yang Yang, Yufeng Liang, Zigui Zhang, Xiaohong Xu*. Anti-androgenic effects of bisphenol-A on spatial memory and synaptic plasticity of the hippocampus in mice. Horm & Behav. 2017, 93:151-158

4 Xiaowei Chen, Yu Wang, Fang Xu, XiaofeiWei, Junfang Zhang, Chuang Wang, HuaWei, Shujun Xu, Peiyun Yan, Wenhua Zhou, Istvan Mody, Xiaohong Xu*, QinwenWang*. The rapid effect of bisphenol-A on long-term otentiation in hippocampus involves estrogen receptors and ERK activation. Neural Plasticity. 2017,

5 Ran Wang, Xiaohong Xu*, Huifang Weng, Shengyao Yan, Yangyang Sun. Effects of early pubertal exposure to di-(2-ethylhexyl) phthalate on social behavior of mice. Horm & Behav. 2016, 80, 117-124

6 Ran Wang, Xiaohong Xu*, Qingjie Zhu. Pubertal exposure to di-(2-ethylhexyl) phthalate influences social behavior and dopamine receptor D2 of adult female mice. Chemosphere. 2016, 144, 1771-1779

7 Yuhua Dai, Yanling Yang, Xiaohong Xu*, Yizhong Hu. Effects of uterine and lactational exposure to di-(2-ethylhexyl) phthalate on spatial memory and NMDA receptor of hippocampus in mice. Horm & Behav. 2015, 71, 41-48

8 Xiaohong Xu* Yanling Yang, Ran Wang, Yu Wang, Qin Ruan, Yang Lu. Perinatal exposure to di-(2-ethylhexyl) phthalate affects anxiety- and depression-like behaviors in mice. Chemosphere. 2015, 124, 22-31

9 Xiaohong Xu*, Ting Gu, Qiaoqiao Shen. Different effects of bisphenol-A on memory behavior and synaptic modification in intact and estrogen-deprived female mice. J Neurochemistry. 2015, 132(5), 572-582.

10 Xiaohong Xu*, Fangni Dong, Yanling Yang, Yu Wang, Ran Wang, Xiuying Shen. Sex-specific effects of long-term exposure to bisphenol-A on anxiety- and depression-like behaviors in adult mice. Chemosphere. 2015, 120, 258-266

11 Xiaohong Xu*, Yang Lu, Guangxia Zhang, Lei Chen, Dong Tian, Xiuying Shen, Yanling Yang, Fanni Dong. Bisphenol A promotes dendritic morphogenesis of hippocampal neurons through estrogen receptor- mediated ERK1/2 signal pathway. Chemosphere. 2014; 96(8):129-137

12 Qin Zhang, Xiaohong Xu*, Tao Li, Yang Lu, Qin Ruan, Yingjun Lu, Qinwen Wang, Fangni Dong, Yanling Yang, Guangxia Zhang. Exposure to bisphenol-A affects fear memory and histone acetylation of the hippocampus in adult mice. Horm & Behav. 2014, 65(2):106–113.

13 Xiaohong Xu*, Yang Lu, Guangxia Zhang, Lei Chen, Dong Tian, Xiuying Shen, Yanling Yang, Fanni Dong. Bisphenol A promotes dendritic morphogenesis of hippocampal neurons through estrogen receptor-mediated ERK1/2 signal pathway. Chemosphere. 2014, 96(8): 129-137

14 Xiaohong Xu*, Xingyi Liu, Qin Zhang, Guangxia Zhang, Yingjun Lu, Qin Ruan, Fangni Dong, Yanling Yang. Sex-specific effects of bisphenol-A on memory and synaptic structural modification in hippocampus of adult mice. Horm & Behav. 2013, 63:766–775.

15 Xiaohong Xu*, Lingdan Xie, Xing Hong, Qin Ruan, Hongfei Lu, Qin Zhang, Guangxia Zhang, Xingyi Liu. Perinatal exposure to bisphenol-A inhibits synaptogenesis and affects the synaptic morphological development in offspring male mice. Chemosphere. 2013, 91(8):1073-1081

16 Xiaohong Xu*, Xing Hong, Lingdan Xie, Tao Li, Yujie Yang, Qin Zhang,Guangxia Zhang, Xingyi Liu. Gestational and lactational exposure to bisphenol-A affects anxiety- and depression-like behaviors in mice. Horm & Behav. 2012, 62:480-490

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