邵勇
发布时间: 2014-03-04 浏览次数: 3266
 

基本资料

邵勇

江师范大学物理化学研究所研究员,双龙学者特聘教授,/博士生导师,浙江省新世纪151人才工程第三层次入选者20019月-200412月,中国科学院长春应用化学研究所电分析化学国家重点实验室获博士学位。20052月-20063月,获法国教育部资助,在法国Université Louis Pasteur从事博士后研究,20065月-20085月,获日本JSPS资助,在Tohoku University从事博士后研究。

学术兴趣及主要研究方向

l基于核酸的光/电生物传感器

l核酸结构的小分子识别

l荧光纳米材料及超分子分析应用

l天然小分子靶标核酸特异性

近期主持的科研项目

1.人类端粒G-四链体碱基损伤缺失位点的选择性识别及回稳研究,国家自然科学基金,2017-2020,主持;

2.人类端粒G-四链体脱碱基位点的小分子选择性识别及结构稳定化研究,国家自然科学基金,2016-2016,主持;

3.DNA脱碱基位点的药物小分子识别:电化学研究及其作用模式分析,国家自然科学基金,2011-2013主持;

4.核酸非经典结构光/电精准识别及传感应用研究,浙江师范大学2017年高端科研项目培育资助项目,主持;

5.植物提取物新型核酸染色剂的筛选及应用研究,浙江省科技厅公益性技术应用研究计划项目,2014-2015,主持;

6.基因损伤碱基缺失的靶向识别生物传感研究,浙江省自然科学基金(杰出青年科学基金项目), 2012-2015,主持;

7.药物与DNA非碱基位点的特异性相互作用研究,浙江省科技厅钱江人才计划项目,2009-2010主持;

8.基于核酸脱碱基位点的有机小分子识别及其分析方法探索,教育部留学回国人员科研启动基金,主持

9.药物小分子识别核酸AP site的电化学研究,国家重点实验室开放基金,主持;

10.法国教育部博士后研究基金,日本JSPS合作研究基金,合作主持;

11.DNA碱基损伤缺失的中性红识别,国家级大学生创新创业计划项目,2012-2013,指导教师。

近期发表的主要论文

1.Molecular recognition of hybrid-2 human telomeric G-quadruplex by epiberberine: insights into conversion of telomeric G-quadruplex structures,Angewandte Chemie International Edition, 2018, 57, 10888–10893

2.G-quadruplex DNA with an apurinic site as a soft molecularly imprinted sensing platform,Analytical Chemistry, 2018, 90, 55525556

  

3.Highly sensitive and selective sensor for sunset yellow based on molecularly imprinted polydopamine-coated multi-walled carbon nanotubes,Biosensors and Bioelectronics, 2018, 100, 565570

4.Adaptively recognizing parallel-stranded duplex structure for fluorescent DNA polarity analysis,Analytical Chemistry, 2017,89, 86048608

5.Prototropically allosteric probe for superbly selective DNA analysis,Analytical Chemistry, 2017,89, 92999306

6.DNA duplex engineering for enantioselective fluorescent sensor,Analytical Chemistry, 2017,89, 21812185

 

7.Human telomeric hybrid-2-over-hybrid-1 G-quadruplex targeting and a selective hypersaline-tolerant sensor using abasic site-engineered monomorphism,Analytica Chimica Acta, 2017, 964, 161169

  

8.Fluorescently sensing DNA triplex assembly using an isoquinoline alkaloid as selector, stabilizer, inducer, and switch-on emitter,Chemistry- An Asian Journal, 2016, 11, 20412048

9.Triggered excited-state intramolecular proton transfer fluorescence for selective triplex DNA recognition,Analytical Chemistry, 2015,87, 1162011624

  

10.Selective lighting up of epiberberine alkaloid fluorescence by fluorophore-switching aptamer and stoichiometric targeting of human telomeric DNA G-quadruplex multimer,Analytical Chemistry, 2015,87, 730737

  

 

11.Molecular rotor-based fluorescent probe for selective recognition of hybrid G-quadruplex and as a K+ sensor,Analytical Chemistry, 2014, 86,16221631.

  

12.Ag nanoclusters as probes for turn-on fluorescence recognition of TpGdinucleotide with a high selectivity, Analytica Chimica Acta, 2014,850, 7884

  

13.Specific recognition of DNA bulge sites by in-situ grown fluorescent Ag nanoclusters with high selectivity,Dalton Transactions,2014, 43, 15341541.

   

14.Highly thymine-dependent formation of fluorescent copper nanoparticles templated by ss-DNA,Nanotechnology, 2013, 24, 345502. (http://nanotechweb.org/cws/article/lab/54322报道).

15.DNA-hosted fluorescent gold nanoclusters: sequence-dependent formation,Nanotechnology, 2013, 24, 015503 (http://nanotechweb.org/cws/article/lab/51763报道).

  

 

16.Base-stacking-determined fluorescence emission of DNA abasic site-templated silver nanoclusters,Langmuir, 2012, 28, 1531315322(封面文章报道)

  

17.Gap site-specific rapid formation offluorescent silver nanoclusters for label-free DNAnucleobase recognition,Analytica Chimica Acta,2012, 724, 8691

  

   


联系方式

l通讯地址:浙江省金华市迎宾大道688号浙江师范大学物理化学研究所220

编:321004

lEmailyshao@zjnu.cn